CALL FOR PAPERS Endocrine and Metabolic Dysfunction during Aging and Senescence Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle
نویسندگان
چکیده
Craig Porter, Nicholas M. Hurren, Matthew V. Cotter, Nisha Bhattarai, Paul T. Reidy, Edgar L. Dillon, William J. Durham, Demidmaa Tuvdendorj, Melinda Sheffield-Moore, Elena Volpi, Labros S. Sidossis, Blake B. Rasmussen, and Elisabet Børsheim Department of Surgery, University of Texas Medical Branch, Galveston, Texas; Shriners Hospitals for Children, Galveston, Texas; Departments of Pediatrics and Geriatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas; Arkansas Children’s Hospital Research Institute, and Arkansas Children’s Nutrition Center, Little Rock, Arkansas; Department of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, Texas; and Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas
منابع مشابه
CALL FOR PAPERS Endocrine and Metabolic Dysfunction During Aging and Senescence Late-onset caloric restriction alters skeletal muscle metabolism by modulating pyruvate metabolism
Chiao-nan (Joyce) Chen, Shang-Ying Lin, Yi-Hung Liao, Zhen-jie Li, and Alice May-Kuen Wong Department of Physical Therapy, Medical School, Chang Gung University, Tao-Yuan, Taiwan; Healthy Aging Research Center, Chang Gung University, Tao-Yuan, Taiwan; Department of Exercise and Health Science, College of Human Development and Health, National Taipei University of Nursing and Health Sciences, Ta...
متن کاملMitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle.
Mitochondrial health is critical to physiological function, particularly in tissues with high ATP turnover, such as striated muscle. It has been postulated that derangements in skeletal muscle mitochondrial function contribute to impaired physical function in older adults. Here, we determined mitochondrial respiratory capacity and coupling control in skeletal muscle biopsies obtained from young...
متن کاملGeneration and bioenergetic analysis of cybrids containing mitochondrial DNA from mouse skeletal muscle during aging
Mitochondrial respiratory chain defects have been associated with various diseases and normal aging, particularly in tissues with high energy demands including skeletal muscle. Muscle-specific mitochondrial DNA (mtDNA) mutations have also been reported to accumulate with aging. Our understanding of the molecular processes mediating altered mitochondrial gene expression to dysfunction associated...
متن کاملCALL FOR PAPERS Endocrine and Metabolic Dysfunction during Aging and Senescence MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance
Oh Sung Kwon, Ruth E. Tanner, Katherine M. Barrows, Marah Runtsch, J. David Symons, Thunder Jalili, Benjamin T. Bikman, Donald A. McClain, Ryan M. O’Connell, and Micah J. Drummond Departments of Physical Therapy, Pathology and Exercise and Sport Science and Divisions of Nutrition and Diabetes, Metabolism and Endocrinology, University of Utah, Salt Lake City, Utah; and Department of Physiology a...
متن کاملAging skeletal muscle mitochondria in the rat: decreased uncoupling protein-3 content.
The goal of the present study was to discern the cellular mechanism(s) that contributes to the age-associated decrease in skeletal muscle aerobic capacity. Skeletal muscle mitochondrial content, a parameter of oxidative capacity, was significantly lower (25 and 20% calculated on the basis of citrate synthase and succinate dehydrogenase activities, respectively) in 24-mo-old Fischer 344 rats com...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2015